1H/X and 1H/19F MRI Volume Coils

¹H/X and ¹H/¹⁹F MRI Volume Coils

Mouse Coils – Rat Coils – Rabbit Coils -Primate Coils – Custom Coils

Dual-frequency MR Coils enable MR spectroscopy and imaging techniques, including hyperpolarized nuclei.  Detailed full-wave simulations ensure the highest sensitivity, homogeneity, and isolation between channels.  B₁ field maps and SAR maps included with each coil.  Flexible design can be customized for your application and MR system.

• Efficient, easy to tune and match over a broad range of sample loadings.
• Each channel for TxRx.
• For observe / decouple – with both channels simultaneously.
• For interleaved acquisitions – with each channel used sequentially.
• Robust design, mechanical stability.
  
  

Low frequency tuning is changed with inserts.

A 38 mm ID ¹H/X for 9.4 T. 

Examples of dual-frequency coils we have supplied (ID x RF length):

• 65 x 52 mm, ¹H/X, (X=¹³C, ¹⁵N),
  @ 3 T; 1.5 T; 1 T; 0.5 T; and 0.3 T.
• 45 x 36 mm, ¹H/X (X=³¹P, ¹³C), @ 7 T.
• 38 x 34 mm, ¹H/X, (X=³¹P, ¹³C), @ 9.4 T.
• 25 x 22 mm, ¹H/X, (X=³¹P, ¹³C), @ 9.4 T.
• 25 x 22 mm, ¹H/¹³C, @ 1 T.
• 200 x 160 mm, ¹H/²³Na, @7 T.
• 38 x 55 mm, ¹H/¹⁹F, @ 7 T.
• 32 x 25mm, ¹H/¹⁹F, @9.4T
  

65 x52 mm 1H/X Dual Freq Coils

A Doty 1H/19F Dual Frequency 32 x25 mm Litzcage module with user incorporated animal bed (Friedrich-Schiller Univ., Jena, Germany).

Mouse Images Obtained with a Doty ¹H/¹⁹F 38 mm Volume Coil

Spatiotemporal in vivo pO₂ tracking and clustering of biomaterial implants in mouse.   Top:  in vivo slice-by-slice fused MRI images, collected with 7 T Doty H/F module, of fluorocapsule distribution (¹⁹F-MRI, red) and soft tissue anatomy (¹H-MRI, grayscale) at day 1 postimplantation for 1.5 mm fluorocapsules implanted in a healthy mouse.  Bottom:  Calculated pO₂ spatial color maps (brighter colors correspond to decreased pO₂).   Spanoudaki V, Doloff JC, Huang W, Norcross SR, Farah S, Langer R, Anderson DG.  Simultaneous spatiotemporal tracking and oxygen sensing of transient implants in vivo using hot-spot MRI and machine learning.  Proc Natl Acad Sci U S A. 2019 Mar 12; 116(11):4861-4870.

Pantom Images from a Dual Frequency ¹H/¹⁹F 32 mm Volume Coil.

9.4 T 1H and 19F images of tubes of water, Isoflurane, and Galden™ PFPE (perfluoropolyether) phantoms. Accordingly, the water sample is bright in the 1H scan and invisible on the 19F channel; Isoflurane, with a mixture of 19F and 1H, is visible on both channels; the 100% fluorinated PFPE is invisible on the 1H channel and bright on the 19F channel. Note that the artifacts/ghosting effect appearing for the PFPE tube is not from the coil, but rather is due to multiple 19F resonance frequencies (and a large 19F chemical shift) which causes multiple (ghost-like) images. Localization is excellent on both channelsHerrmann K-H ¹*, Pechmann N ^1,2, Reichenbach JR ¹,

¹ Medical Physics Group, IDIR, University Hospital Jena – Friedrich-Schiller University, Jena, Germany.
² University of Applied Sciences “Ernst Abbe”, Dept. of Medical Technology and Biotechnology, Jena, Germany.
*corresponding author