Unique 15.2 T Dual Frequency 1H-19F/X MRI Coils
Doty’s first 15.2 T Coil was delivered to the Weizmann Institute just before the ENC in 2024. This unique MRI coil was for mouse body (or rat brain). The high frequency (650 MHz 1H) and tight spacing (59 mm OD with two coils and a 36 mm ID) made this coil quite challenging! Tuning included: 1H-19F (tunable from 1H to 19F) and multinuclear X that included low gamma nuclei: 23Na,13C, 2H, 17O, 15N, and 14N.
A 36 mm ID x 35 mm FOV allows surface coil receive, when desired.
Results are presented below.
“The probe works very nicely – and it’s really a relief to be able to target the full pregnant animal on 1H and 2H without having to search positions fetus-by-fetus with a surface coil.” – Lucio
(A joint ENC poster, Doty Scientific and Weizmann Institute, was presented in 2025.
Click here to view the poster. )
MRI 1H and 2H results on a pregnant mouse (E16.5) were recorded in ~2 minute intervals following injection of saline D2O, providing water transport information across the placentas and into individual fetal organs at a level never before seen.
Images courtesy of Clore Institute for High Magnetic Field Imaging and Spectroscopy,
Weizmann Institute.
Circled in blue and yellow are two fetuses; orange and purple indicate placentas.
