Results: 1H/19F MRI Imaging
A Simple-tune Preclinical 19F RF Volume Coil
- Efficient, easy to tune and match over a broad range of sample loading.
- Each channel for TxRx and linearly polarized.
- For observe / decouple – with both channels used simultaneously.
- For interleaved acquisitions – with each channel used sequentially.
- Robust design and mechanical stability
Pictured is a Doty 1H/19F Dual Frequency 32 mm Litzcage module. Shown with user incorporated animal bed. Photo courtesy of Friedrich-Schiller Univ., Jena, Germany.
Mouse Images Obtained with a Doty 1H/19F 38 mm Volume Coil
Spatiotemporal in vivo pO2 tracking and clustering of biomaterial implants in mouse. Top: in vivo slice-by-slice fused MRI images, collected with 7 T Doty H/F module, of fluorocapsule distribution (19F-MRI, red) and soft tissue anatomy (1H-MRI, grayscale) at day 1 postimplantation for 1.5 mmfluorocapsules implanted in a healthy mouse. Bottom: Calculated pO2 spatial color maps (brighter colors correspond to decreased pO2).
Spanoudaki V, Doloff JC, Huang W, Norcross SR, Farah S, Langer R, Anderson DG. Simultaneous spatiotemporal tracking and oxygen sensing of transient implants in vivo using hot-spot MRI and machine learning. Proc Natl Acad Sci U S A. 2019 Mar 12; 116(11):4861-4870.
