NMR Products


Dramatic Advances in NMR of Insoluble Proteins

Dramatic Advances in NMR of Insoluble Proteins 3Hz 1H linewidth on solid protein GB1. This 1H spectrum was taken at 500 MHz with 2H decoupling using our 1H/X/Y/Z MAS probe. The region shown is for methyl protons with 2H decoupling and water suppression. Linewidths at half maximum are shown in Hz. (Note the major linewidth reduction from 10-kHz 2H decoupling.) Bibhuti Das and Paul Ellis, Doty Scientific, Inc., and Professor Leonard Mueller, Univ. of CA ...


SERMACS/Doty Scientific Facility Tour

Doty Scientific had a tour our NMR facility on Tuesday October 25th. This activity was planned in coordination with the Southeastern Regional Meeting of ACS (SERMACS) in Columbia SC, in October, 2016. We provided lunch, a short presentation, plus a tour of the plant and our NMR Lab.


Guide to Simulating NMR Probe Circuits

We begin a series of articles on “Guide to Simulating NMR Probe Circuits”. We will strive to keep the perfect balance between in-depth, tutorial, and detailed. We plan to present many state-of-the-art circuits of interest to researchers in liquids and solids NMR and MRI over the next several years. This series, which will include circuit simulation files ready to run (if you have a Genesys license), will be fully available on our website, and a brief summary of each article ...


CryoMAS-DNP Talk at the SEMRC 2014 Southeastern Magnetic Resonance Conference

Dr. David Doty will be delivering a talk at the SEMRC on the Doty Scientific's recent progress in two major development projects - a novel cavity for H/X/Y DNP promising huge gains in microwave efficiency, and a CryoMAS-DNP probe capable of closed-loop spinning with helium gas down to 30 K, for enormous gain in S/N compared to prior MAS-DNP technology. The talk will include the latest NMR test data, showing success in what has been an epic journey over the ...


No Need to ‘Panic’ – It’s almost ENC Time!

No need to ‘Panic’ – It’s almost ENC Time! The PANIC Conference (Practical Applications in NMR in Industry) in Charlotte, NC in February lived up to the title. Laura reported that the scientific program was well organized with stimulating topics presented in talks, workshops, and poster sessions. Attendee numbers doubled from last year. Thanks to everyone who stopped by to discuss products or say hello to Laura Holte. It’s that time ...


Introducing Doty SNR Applet

NMR Signal to Noise Ratio - SNR Applet Doty Scientific has produced an applet that allows a customer to compare the signal-to-noise ratio of a DSI probe to the SNR of any other well-tested probe. This will be the first time a customer can compare any probe, with any sample and any test conditions, to any Doty probe. The ratio of signal acquisition times of the two probes is also calculated as (ratio of ...


New Faces at Doty Scientific

We are pleased to have these new faces at Doty Scientific to help with our increased work load. Join us to welcome: Eshwarprasad Thirunavukarasu, MSME Eshwar joined us after his graduation from the University of South Carolina (our USC).         Brian Mercurio, Physicist, Ph. D. Brian is a graduate of Ohio State University. He joined us after a postdoc at the University of South Carolina.         Manlai Liang,Physicist, Ph.D. Manlai recently ...


Your wishlist for 2014?

In the last two months, we were privileged to participate in the Southeastern NMR conference in Tallahassee, Florida in the US, and the Asian Pacific NMR & ANZMAG conference in Brisbane Australia.               Discussions about DNP were ...


BMAX Probe 100 Times Faster

Could a BMAX Probe be 100 Times Faster than your current solids probe? Possibly. How could that be true? The following is one of the most useful expressions for predicting S/N following a single π/2 pulse at thermal equilibrium: The parameters VS/τ90P1/2 are determined by the NMR probe, and for 13C in Doty's 3 mm D1-3 at 11.7 T, it is ~1 (common units). ...


Doty Scientific awarded SBIR Research Grant from NIH for development of a 30 K MAS-DNP probe

Doty Scientific was awarded a Small Business Innovation Research (SBIR) research grant from the National Institutes of Health (NIH) for development of a 30 K MAS-DNP probe. The award started on September 30, 2013. This SBIR project will enable 30 K MAS-DNP operation by developing: (A) the needed high-stability 30 K helium spinner technology, (B) the needed high- efficiency closed-loop cryogenic helium recycling system, and (C) the complete quad-resonance (1H-13C-15N-electrons) DNP probe with auto sample exchange and extended variable temperature (XVT) operation for ...

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